Growth hormone axis
GHRP-6 Price Comparison
Also referred to as: Growth Hormone Releasing Peptide-6 · Growth Hormone Releasing Hexapeptide · GHRP6 · GH-Releasing Peptide-6
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For in-vitro laboratory research only
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Research profile
About GHRP-6 in the lab
One of the earliest synthetic growth-hormone secretagogues. It remains a classical reference ligand for GHS-R1a pharmacology.
Proposed mechanism
Activates the growth hormone secretagogue receptor (GHS-R1a), the receptor for ghrelin, stimulating GH release from pituitary somatotrophs and acting on hypothalamic appetite circuits in models.
Structure note
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2.
Amino-acid sequence (one-letter)
H?WAW?FK?
Typical research themes
- GHS-R1a pharmacology
- Structure–activity relationships
- Historical reference compound
Key references
- On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. · Endocrinology (1984)
- Growth hormone-releasing peptide (GHRP). · Cellular and molecular life sciences : CMLS (1998)
- Ghrelin is a growth-hormone-releasing acylated peptide from stomach. · Nature (1999)
- Peptidomimetic regulation of growth hormone secretion. · Endocrine reviews (1997)
This profile is a short, general summary of publicly discussed science. It is not exhaustive, not peer-reviewed by PeptideCompare, and is not medical advice. PeptideCompare provides no dosing, protocol or usage guidance — nothing here is for human or veterinary use.
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