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Growth hormone axis

IGF-1 DES (1-3) Price Comparison

N-terminally truncated IGF-1 with reduced binding-protein affinity.

Also referred to as: Insulin-Like Growth Factor 1 DES (1-3)

UK supplier comparison

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For in-vitro laboratory research only

IGF-1 DES (1-3) is listed here as a research material. It is not for human or veterinary consumption, and nothing on this page is medical advice or dosing guidance. PeptideCompare is paid by flat supplier fees — never by sales commission or referral — so a price ranks by its number, not by who pays. We do not sell, test or verify any product, and quality or CoA labels are suppliers’ own claims. Always check the final price, documentation and legality with the supplier yourself.

Research profile

About IGF-1 DES (1-3) in the lab

IGF-1 DES (1-3) lacks the first three amino acids of IGF-1. That small change sharply lowers binding to IGF binding proteins, so more of it stays free and active in cell culture.

Proposed mechanism

Activates the IGF-1 receptor tyrosine kinase, triggering PI3K–Akt and MAPK pathways; reduced IGFBP sequestration gives higher apparent potency in vitro.

Typical research themes

  • IGF-1 receptor signalling
  • IGFBP binding
  • Cell proliferation assays

This profile is a short, general summary of publicly discussed science. It is not exhaustive, not peer-reviewed by PeptideCompare, and is not medical advice. PeptideCompare provides no dosing, protocol or usage guidance — nothing here is for human or veterinary use.

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