Immune signalling
KPV Price Comparison
Also referred to as: Lysine-Proline-Valine (KPV Tripeptide) · Anti-Inflammatory Tripeptide
UK supplier comparison
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For in-vitro laboratory research only
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Research profile
About KPV in the lab
KPV (Lys-Pro-Val) is the last three amino acids of alpha-melanocyte-stimulating hormone. It keeps much of alpha-MSH's anti-inflammatory activity in models without its pigment effects, and is studied in intestinal and skin inflammation research.
Proposed mechanism
Taken into cells via the PepT1 transporter in intestinal epithelium, it is reported to reduce NF-κB activation and pro-inflammatory cytokine expression; melanocortin-receptor involvement is debated.
Structure note
Tripeptide (3 amino acids).
Typical research themes
- NF-κB signalling
- PepT1 transport
- Colitis models
Key references
- The melanocortin system in control of inflammation. · TheScientificWorldJournal (2010)
This profile is a short, general summary of publicly discussed science. It is not exhaustive, not peer-reviewed by PeptideCompare, and is not medical advice. PeptideCompare provides no dosing, protocol or usage guidance — nothing here is for human or veterinary use.
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