Immune signalling
PNC-27 Price Comparison
Also referred to as: PNC-27 (p53-Derived Anticancer Peptide) · PNC27 · p53-Penetratin Chimeric Peptide · Anti-Cancer Peptide
UK supplier comparison
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For in-vitro laboratory research only
PNC-27 is listed here as a research material. It is not for human or veterinary consumption, and nothing on this page is medical advice or dosing guidance. PeptideCompare is paid by flat supplier fees — never by sales commission or referral — so a price ranks by its number, not by who pays. We do not sell, test or verify any product, and quality or CoA labels are suppliers’ own claims. Always check the final price, documentation and legality with the supplier yourself.
Research profile
About PNC-27 in the lab
PNC-27 links a sequence from the p53 protein's HDM-2 binding domain to a membrane-penetrating leader sequence. In cell culture it has been reported to damage cancer-cell membranes selectively. Evidence is preclinical only.
Proposed mechanism
Proposed to bind HDM-2 expressed on cancer-cell membranes, forming pores that cause rapid necrosis, while sparing normal cells that lack membrane HDM-2.
Structure note
Chimeric peptide.
Typical research themes
- Membrane-active peptides
- HDM-2 targeting
- Cancer-cell lines
This profile is a short, general summary of publicly discussed science. It is not exhaustive, not peer-reviewed by PeptideCompare, and is not medical advice. PeptideCompare provides no dosing, protocol or usage guidance — nothing here is for human or veterinary use.
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