Growth hormone axis
GDF-8 (Myostatin) Price Comparison
Also referred to as: Growth Differentiation Factor 8 (Myostatin)
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For in-vitro laboratory research only
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Research profile
About GDF-8 (Myostatin) in the lab
Myostatin (GDF-8) is secreted mainly by skeletal muscle and acts as a brake on muscle growth; natural loss-of-function mutations cause markedly increased muscle mass in several species. Recombinant protein is used as a reference ligand in receptor and inhibitor studies.
Proposed mechanism
Released from its latent complex, mature myostatin binds ActRIIB with ALK4/5 co-receptors and activates SMAD2/3, suppressing myogenic gene programmes.
Typical research themes
- Ligand–receptor assays
- SMAD2/3 signalling
- Muscle growth regulation
This profile is a short, general summary of publicly discussed science. It is not exhaustive, not peer-reviewed by PeptideCompare, and is not medical advice. PeptideCompare provides no dosing, protocol or usage guidance — nothing here is for human or veterinary use.
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